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DNA gyrase - Wikipedia, the free encyclopedia (Search Map)
Many antibiotics work by attacking bacterial DNA gyrase. ... The ability of gyrase to relax positive supercoils comes into play during DNA replication. ...
Type II topoisomerase - Wikipedia, the free encyclopedia (Search Map)
For example, DNA gyrase, a type II topoisomerase observed in E. coli and most ... that gyrase, which forms a 140 base-pair footprint, wraps DNA allowing it ...
DNA gyrase - definition of DNA gyrase by the Free Online Dictionary ... (Search Map)
Information about DNA gyrase in the free online English dictionary and ... identified by using flaB and DNA gyrase B subunit gene (gyrB) sequencing analysis. ...
Effect of different classes of inhibitors on DNA gyrase from ... (Search Map)
Thus, DNA gyrase appears to be an ideal target for antibacterial drugs. DNA gyrase cleaves a double strand, passes another duplex through it and reseals ...
Dissection of the Nucleotide Cycle of B. subtilis DNA Gyrase and its ... (Search Map)
B. subtilis DNA gyrase is highly homologous to its well-studied Escherichia ... efficient in negative supercoiling as the E. coli DNA gyrase. ...
GyrI: a counter-defensive strategy against proteinaceous inhibitors of ... (Search Map)
DNA gyrase is distinct from all other topoisomerases in its ability to introduce ... These inhibitors stabilize gyrase–DNA covalent complexes, which are converted to ...
Both DNA gyrase and reverse gyrase are present in the hyperthermophilic ... (Search Map)
Here we show that it contains also a DNA gyrase. ... Reverse gyrase is a unique combination of a classical type I DNA topoisomerase ...
Interaction between DNA Gyrase and Quinolones: Effects of Alanine ... (Search Map)
DNA gyrase is a target of quinolone antibacterial agents, but the molecular ... DNA gyrase consists of two proteins, GyrA and GyrB, which form an A2B2 complex ...
The DNA Gyrase-Quinolone Complex. ATP HYDROLYSIS AND THE MECHANISM OF ... (Search Map)
Quinolone binding to the gyrase-DNA complex induces a conformational change that ... DNA gyrase is the intracellular target of the quinolone group of ...
DNA Gyrase, Topoisomerase IV, and the 4-Quinolones (Search Map)
Gyrase controls DNA supercoiling and re ... trapping of gyrase and topoisomerase IV on DNA probably ... gyrase removes negative supercoils from DNA (47, 189). Since ...