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Preclinical Antitumor Activity of BMS-214662, a Highly Apoptotic and ... (Search Map)
BMS-214662 is a potent and selective inhibitor of farnesyltransferase (FTI) ... In soft agar growth assays, BMS-214662 showed good potency in inhibiting H-ras ...
Blood -- BMS-214662 potently induces apoptosis of chronic myeloid ... (Search Map)
Prepublished online as a Blood First Edition Paper on December 21, 2007; DOI 10.1182/blood-2007-09-112573. This Article. Services. Citing Articles. Google Scholar ...
Definition of BMS-214662 - NCI Dictionary of Cancer Terms (Search Map)
The search textbox has an autosuggest feature. When you enter three or more ... BMS-214662. A substance that is being studied in the treatment of cancer. ...
ALS TDI (Search Map)
The ALS Therapy Development Institute is dedicated to discovering and developing ... BMS-214662 is a benzodiazepine derivative, an ... BMS ...
Preclinical Antitumor Activity of BMS-214662, a Highly Apoptotic and ... (Search Map)
BMS-214662 is a potent and selective inhibitor of farnesyltransferase (FTI). In rodent ... In soft agar growth assays, BMS-214662 showed good potency ...
Definition of BMS-214662 - National Cancer Institute Drug Dictionary (Search Map)
BMS-214662. A nonsedating benzodiazepine derivative with potential ... Farnesyltransferase inhibitor BMS-214662 inhibits the enzyme farnesyltransferase ...
Blood -- BMS-214662 potently induces apoptosis of chronic myeloid ... (Search Map)
In contrast, BMS-214662, alone or in combination with IM or dasatinib, potently ... BMS-214662 was cytotoxic against CML blast crisis stem/progenitor cells, ...
Phase I Clinical Trial of the Farnesyltransferase Inhibitor BMS-214662 ... (Search Map)
BMS-214662 is a nonpeptidomimetic FT inhibitor composed of a benzodiazepine core ... Fig. 1. Chemical structure of BMS-214662. ...
A Phase I Trial of the Novel Farnesyl Protein Transferase Inhibitor ... (Search Map)
BMS-214662 is a potent benzodiazepine-like nonthiol, nonpeptide, competitive ... BMS-214662 produces rapid tumor regression and cures in various human xenograft ...
Farnesyltransferase Inhibitor BMS-214662 Induces Apoptosis in Myeloma ... (Search Map)
Low concentrations of BMS-214662 efficiently inhibited protein farnesylation but ... However, Z-VAD-fmk did not prevent BMS-214662–induced Bax and Bak activation and ...